A New Strategy for Getting More People Vaccinated Faster

If the average benefit from a booster is only 5%,(increasing efficacy from 90 to 95%), then intuitively it seems logical that this dose is better used by giving it to another individual without any vaccination to increase their immunity from 0 to 90%.

A number of researchers have proposed getting first COVID vaccine doses to as many people as possible right away, instead of holding back vaccine to give as 2nd doses later. A new paper released today estimates that we could immunize everyone much more quickly given this approach.

Most of the protection comes from the first dose, so getting more first doses out should be able to protect more people than reserving doses so people can get a second one.

The clinical trials did not delay 2nd doses, so this approach is somewhat speculative. However, the paper shows that even if immune function drops off significantly with just one dose, getting more doses out faster leads to faster herd immunity.

This is being done in Canada and the UK. Former FDA Commissioner Scott Gottlieb favors it. It may be time to give this innovative approach a try in the United States.

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